Kalendář akcí VŠCHT Praha

Antibiotic Resistance in the Environment: Why it is important?


Datum: 18.11.2020  10:00 - 11:30      
Místo konání: online
Kategorie: Věda
Typ akce: Pozvánka, Přednáška
Přednášející: Célie M. Manaiay, CBQF-Centro de Biotecnologia e Química Fina – Laboratório Associado
Jazyk akce: EN

Acquired antibiotic resistance emerged with the first therapeutic uses of antibacterial drugs, more than 80 years ago. Over decades antibiotic resistant bacteria were reported in clinical settings and considered a major problem spreading in hospitals, mainly among immunocompromised and debilitated patients.

This situation has evolved unfavourably and antibiotic resistant infections can affect anyone, no matter the age, health condition or the country where one lives. In part this is due to the fact that antibiotic resistance is no longer confined to clinical settings, it is spread over humans, animals, plants and the environment. A One-Health vision is therefore necessary to better understand how does antibiotic resistance spread from major sources, humans and animals.

The impact of different emission sources on the accumulation and spread of antibiotic resistant bacteria and antibiotic resistance genes in the environment has been mainly assessed based on the abundance and prevalence of these self-replicative biological contaminants. However, there are different reasons to believe that this approach may be of limited value to assess risks. These evidences highlight the uncertainty that hampers the establishment of solid recommendations to control antibiotic resistance dissemination. The understanding of the spread and evolution of antibiotic resistance involves approaches that span the microbial ecology, genetics and physiology.  However, the mitigation of this serious problem clearly overflows the life science domains, requiring the support of areas as diverse as the engineering or the social sciences. 


Célia M. Manaia research interests in the field of antibiotic resistance have been focused on the dissemination of bacteria and genes across the urban water cycle, with a special interest in wastewater systems. She has been involved in multidisciplinary teams who have been interested in measuring antibiotic resistance impacts and in controlling its dissemination through engineering-based solutions. In the last years, she has been involved as a leader or participant in different national and international projects, of basic research, applied research, and mobility/networking with relevant impacts in the area.


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